ACADSTAFF UGM
| Title | : | Association of vitamin D deficiency with cardiovascular disease risk in children: Implication for the Asia Pacific Region |
| Author | : |
Prof. dr. Indah Kartika Murni, M.Kes., Sp.A(K)., Ph.D. (1) Dian Caturini Sulistyoningrum, B.Sc., M.Sc. (2) dr. Vicka Oktaria, M.P.H., Ph.D (3) |
| Date | : | 2016 |
| Keyword | : | vitamin D deficiency, sunlight exposure, cardiovascular disease risk, children vitamin D deficiency, sunlight exposure, cardiovascular disease risk, children |
| Abstract | : | Background and Objectives: Vitamin D deficiency significantly affects cardiovascular disease risk. Cardiovas- cular disease is epidemic in nature. Because the prevalence of cardiovascular disease has been increasing in chil- dren, it has been changing from an adulthood disease to a childhood disease. Therefore, formulating an effective prevention strategy against cardiovascular disease development in children is crucial. Methods and Study De- sign: From PubMed, we identified and reviewed studies evaluating the association of vitamin D deficiency with cardiovascular disease risk in children. Results: The mechanism through which vitamin D protects against cardi- ovascular disease has yet to be fully elucidated. Vitamin D deficiency may be associated with various risk factors for cardiovascular disease that are already manifested in childhood, including obesity, hypertension, dyslipidae- mia, insulin resistance, and metabolic syndrome. Vitamin D deficiency has been associated with cardiovascular disease because it promotes vascular stiffness and calcification, leading to atherosclerosis. However, studies in- vestigating the effectiveness of vitamin D in preventing cardiovascular disease risk by using an ideal study design are scant. Conclusions: Vitamin D deficiency in children may increase cardiovascular disease risk, which tends to manifest in childhood. Because data on the association of vitamin D deficiency with cardiovascular disease risk among children are limited and inconclusive, additional studies are required to investigate this association in chil- dren in general and in a setting with naturally abundant sun exposure. |
| Group of Knowledge | : | Bidang Kedokteran Spesialis Lain Yang Tercantum |
| Original Language | : | English |
| Level | : | Internasional |
| Status | : |
Published
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| No | Title | Action |
|---|---|---|
| 1 |
S8-Asia Pacific Journal of Clinical Nutrition - Vit D review.pdf
Document Type : Bukti Published
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