ACADSTAFF UGM
| Title | : | Bioceramic hydroxyapatite-based scaffold with a porous structure using honeycomb as a natural polymeric Porogen for bone tissue engineering |
| Author | : |
MONA SARI (1) Puspa Hening (2) Dr. Chotimah, M.Si. (3) Prof. drg. Ika Dewi Ana, M.Kes., Ph.D. (4) Prof. Dr. Eng. Yusril Yusuf, S.Si., M.Si., M.Eng. (5) |
| Date | : | 0 2021 |
| Keyword | : | Scaffold, Abalone mussel shells, Honeycomb, Bone tissue engineering,Hydroxyapatite Scaffold, Abalone mussel shells, Honeycomb, Bone tissue engineering,Hydroxyapatite |
| Abstract | : | The application of bioceramic hydroxyapatite (HA) derived from materials high in calcium to tissue engineering has been of concern, namely scaffold. Scaffold pores allow for cell mobility metabolic processes, and delivery of oxygen and nutrients by blood vessel. Thus, pore architecture affects cell seeding efficiency, cell viability, migration, morphology, cell proliferation, cell differentiation, angiogenesis, mechanical strength of scaffolds, and, eventually, bone formation. Therefore, to improve the efficacy of bone regeneration, several important parameters of the pore architecture of scaffolds must be carefully controlled, including pore size, geometry, orientation, uniformity, interconnectivity, and porosity, which are interrelated and whose coordination affects the effectiveness of bone tissue engineering. The honeycomb (HCB) as natural polymeric porogen is used to pore forming agent of scaffolds. It is unique for fully interconnected and oriented pores of uniform size and high mechanical strength in the direction of the pores. The aim of this study was therefore to evaluate the effect of HCB concentration on macropore structure of the scaffolds. |
| Group of Knowledge | : | Fisika |
| Original Language | : | English |
| Level | : | Internasional |
| Status | : |
Published
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