ACADSTAFF UGM
| Title | : | Correlation of HbsAg, HBeAg and HBV DNA Viral Load in Chronic Hepatitis B Patients |
| Author | : |
Dr. dr. Umi Solekhah Intansari, M.Kes., Sp.PK(K) (3) Prof. dr. Budi Mulyono, Sp.PK.(K).,MM (4) |
| Date | : | 0 2019 |
| Keyword | : | Chronic Hepatitis B, HBsAg, HBeAg, HBV Viral Load Chronic Hepatitis B, HBsAg, HBeAg, HBV Viral Load |
| Abstract | : | Introduction: The high incidence of Hepatitis B infection worldwide causes this to be a universal problem. Diagnosis and monitoring of HBV infection therapy currently uses HBsAg, HBeAg, anti HBe, anti HBc and HBV Viral Load tests. Limitations of the tools and costs of HBV DNA Viral load test causes monitoring of patients with chronic HBV infection is difficult. This study aims to look at the correlation between HBsAg, HBeAg and HBV DNA Viral Load in patients with Chronic Hepatitis B. Method: Chronic Hepatitis B patients who meet the criteria consisted of 232 samples. HBsAg, HBeAg, anti HBe, and HBV DNA Viral Load data were analyzed using the Spearmans Correlation Test and Chi Square Test. There is a significant correlation and relationship if the test p value is <0.05. Results and Discussion: Correlation test results showed a significant positive correlation between HBsAg and HBeAg against HBV DNA, with a role of 28.8% and 60% respectively. There is a significant relationship between HBsAg and HBeAg with HBV DNA. The percentage of subjects with high HBV DNA was found to be higher in subjects with HBsAg and HBeAg who were also higher than in subjects with low HBsAg, HBeAg and anti HBe. Conclusion and Suggestion: In this study, it is concluded that there is a significant positive correlation between HbsAg and HBeAg with HBV Viral Load. HBeAg has the greatest role in HBV DNA. |
| Group of Knowledge | : | Bidang Kedokteran Spesialis Lain Yang Tercantum |
| Original Language | : | English |
| Level | : | Internasional |
| Status | : |
Published
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