ACADSTAFF UGM
| Title | : | Development of Uric acid Sensor Based on Molecularly Imprinted Polymethacrylic Acid-modified Hhanging Mercury Drop Electrode |
| Author | : |
Miratul Khasanah (1) Prof. Drs. Mudasir, M.Eng., Ph.D. (2) Dr. Agus Kuncaka, DEA (3) Dr. Eko Sugiharto DEA (4) |
| Date | : | 25 2012 |
| Keyword | : | Uric acid, sensor, imprinted polymer, methacrylic acid Uric acid, sensor, imprinted polymer, methacrylic acid |
| Abstract | : | Development of uric acid sensor based on molecularly imprinted polymer (MIP) was studied. The sensor was developed by coating the imprinted polymethacrylic acid on the surface of a hanging mercury drop electrode (HMDE) at -1 V (vs. Ag/AgCl) during 60 s. Uric acid was accumulated on the modified electrode at -1 V (vs. Ag/AgCl) during 60 s in acetate buffer pH = 5 and stripped at scan rate of 59 mV/s. Oxidation of uric acid on the surface of modified electrode is irreversible through the diffusion controlled process and polymethacrylic acid is a non-electrical conducting polymer. The current signal obtained from the analysis of uric acid by using HMDE is higher than that of the HMD-polymethacrylic acid (polyMAA), HMD-MIP and HMD-non imprinted polymer (NIP) electrode. The HMD-MIP has demonstrated its performance as a sensitive voltammetric sensor for uric acid. The modified electrode has been tested for the determination of uric acid in the serum sample with recovery percentage of 95.7% (n = 2). The limit of detection obtained was 6.0 × 10-10 M |
| Group of Knowledge | : | Kimia |
| Original Language | : | English |
| Level | : | Internasional |
| Status | : |
Published
|
| No | Title | Action |
|---|---|---|
| 1 |
JCCE-Mira-2012.pdf
Document Type : [PAK] Full Dokumen
|
View |
| 2 |
Hal_ Cover JCCE.pdf
Document Type : [PAK] Halaman Cover
|
View |
| 3 |
Development of Uric Acid Sensor Based on Molecularly Imprinted Polymethacrylic Acid-Modified Hanging Mercury Drop Electrode.pdf
Document Type : [PAK] Cek Similarity
|
View |