ACADSTAFF UGM
| Title | : | One Step Synthesis of Symmetrical Amino Azine Derivatives Using Hydrazine Hydrate as a Reagent |
| Author | : |
Prof. Drs. Bambang Purwono, M.Sc., Ph.D. (2) Prof. Dr.rer.nat. Harno Dwi Pranowo, M.Si. (3) |
| Date | : | 20 2020 |
| Keyword | : | Azine, hydrazine hydrate, electron-withdrawing group, Pd/C Azine, hydrazine hydrate, electron-withdrawing group, Pd/C |
| Abstract | : | Symmetrical amino azine derivative compound of 6,6'-((1E,1'E)-hydrazine-1,2-diylidenebis(methanyl-ylidene))bis(3,4-dimethoxyaniline) TM has been synthesized through an unusual reaction route employed benzylidine derivative with some electron-withdrawing groups as intermediate compounds. The target TM compound was prepared by one-pot reaction of the intermediate 2-(4,5-dimethoxy-2-nitrobenzylidene)malononitrile 3 or (E)-1,2-dimethoxy-4-nitro-5-(2-nitrovinyl)-benzene 4 or nitrohydrazone 5 with excess 80% hydrazine hydrate and 10% Pd/C catalyst. However, direct synthesis to produce TM using nitro aryl aldehyde derivatives with 80% hydrazine hydrate and 10% Pd/C catalyst failed to obtain the target compound of TM. |
| Group of Knowledge | : | |
| Level | : | Internasional |
| Status | : |
Published
|