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Title : Prognostic Factors for Survival of Patients with Biliary Atresia Following Kasai Surgery
Author :

SHIEFA ANNISA QISTHI (1) DANIEL S P SARAGIH (2) DAVID WIJAYA SUTOWO (3) Dian Nirmala Sirait (4) PRISCILLIA IMELDA (5) Sagita Mega Sekar Kencana (6) Dr. dr. Akhmad Makhmudi, Sp.B., Sp.BA.,Subsp.D.A(K) (7) Prof. dr. Gunadi, Ph.D, Sp.BA., Subsp.DA(K) (8)

Date : 5 2020
Keyword : Biliary Atresia,Kasai Surgery,Prognostic Factor,Survival Biliary Atresia,Kasai Surgery,Prognostic Factor,Survival
Abstract : Biliary atresia (BA) is a progressive obstruction and fibro-obliteration of the extrahepatic and intrahepatic biliary tract that causes cholestasis jaundice in infants, resulting in biliary cirrhosis and even death in the first year of life if the Kasai procedure is not performed at an earlier age. There are many prognostic factors that could affect the survival of patients with BA after Kasai surgery, however results still show some conflicting findings. A retrospective study was conducted using medical records of patients with BA who underwent Kasai surgery at Dr. Sardjito Hospital, Yogyakarta, Indonesia from June 2012 to April 2018. Twenty-nine BA patients were involved in our study, with 16 males and 13 females. Log-rank analysis showed a significant association between survival rate of BA patients with albumin level 1 month and 3 months after Kasai surgery, with p-values of 0.043 and 0.016, respectively. Interestingly, multivariate analysis revealed that cholangitis tended to have an association with BA patients’ survival (p=0.09). In conclusion, the BA patients’ survival might be affected by the presence of cholangitis after Kasai surgery. Further multicenter studies with a larger sample size are important to verify our results.
Group of Knowledge : Bedah (Umum, Plastik, Orthopaedi, Urologi, Dll)
Original Language : English
Level : Internasional
Status :
Published
Document
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1 Full Doc_Aug 2020_Prognostic Factors for Survival of Patients with Biliary Atresia Following Kasai Surgery.pdf
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2 Prognostic Factors for Survival of Patients with Biliary Atresia Following Kasai Surgery.pdf
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3 42_BuktiKorespondensi_SurvivalBiliaryAtresia.pdf
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