ACADSTAFF UGM

CREATION
Title : Reaction-Diffusion on a Spatial Mathematical Model of Cancer Immunotherapy with Effector Cells and IL-2 Compounds’ Interactions
Author :

SULASRI SUDDIN (1) Dr. Fajar Adi Kusumo, S.Si., M.Si. (2) Dr.rer.nat. Lina Aryati, M.S. (3) Dr. Drs. Gunardi, M.Si. (4)
Date : 24 2021
Keyword : limit cycle, reaction-diffusion,cancer disease, numerical computation limit cycle, reaction-diffusion,cancer disease, numerical computation
Abstract : Immunotherapy is one of the future treatments applicable in most cases of cancer including malignant cancer. Malignant cancer usually prevents some genes, e.g., p53 and pRb, from controlling the activation of the cell division and the cell apoptosis. In this paper, we consider the interactions among the cancer cell population, the effector cell population that is a part of the immune system, and cytokines that can be used to stimulate the effector cells called the IL-2 compounds. These interactions depend on both time and spatial position of the cells in the tissue. Mathematically, the spatial movement of the cells is represented by the diffusion terms. We provide an analytical study for the constant equilibria of the reaction-diffusion system describing the above inter- actions, which show the initial behaviour of the tissue, and we conduct numerical simulation that shows the dynamics along the tissue that represent the immunotherapy effects. In this case, we also consider the steady-state conditions of the system that show the long-time behaviour of these interactions.
Group of Knowledge : Matematika
Original Language : English
Level : Internasional
Status :
Published
Document
No Title Document Type Action
1 Full - 5535447 - Reaction-Diffusion on a Spatial Mathematical Model.pdf
Document Type : [PAK] Full Dokumen
[PAK] Full Dokumen View
2 Reaction-Diffusion on a Spatial Mathematical Model of Cancer Immunotherapy with Effector Cells and IL-2 Compounds’ Interactions.pdf
Document Type : [PAK] Cek Similarity
[PAK] Cek Similarity View
3 210115 - IJDE Correspondences - Reaction-Diffusion on a Spatial Mathematical Model of Cancer Immunotherapy with Effector Cells and IL-2 Compounds Interactions.pdf
Document Type : [PAK] Bukti Korespondensi Penulis
[PAK] Bukti Korespondensi Penulis View