ACADSTAFF UGM
| Title | : | SOME 2-ARYLBENZIMIDAZOLE DERIVATIVES AS AN ANTIMALARIAL AGENT: SYNTHESIS, ACTIVITY ASSAY, MOLECULAR DOCKING AND PHARMACOLOGICAL EVALUATION |
| Author | : |
Prof. Drs. Bambang Purwono, M.Sc., Ph.D. (1) BETA ACHROMI N (2) PANDJI ZAMZAMI FATHURROHMAN (3) JUFRIZAL SYAHRI (4) |
| Date | : | 11 2021 |
| Keyword | : | Antimalarial,2-arylbenzimidazole,Docking,Bioavailability,Plasmodium falciparum. Antimalarial,2-arylbenzimidazole,Docking,Bioavailability,Plasmodium falciparum. |
| Abstract | : | A series of some 2-arylbenzimidazole derivatives have been synthesized from substituted aryl aldehyde and o-phenylenediamine using microwave radiation and tested for its antimalarial activity. The 2-(4-methoxyphenyl)-1H-benzimidazole showed excellent in vitro antimalarial activity toward Plasmodium falciparum (3D7) strain. Molecular docking studies have supported in vitro antimalarial assay. This compound also showed good bioavailability and druglike properties. |
| Group of Knowledge | : | Kimia |
| Original Language | : | English |
| Level | : | Internasional |
| Status | : |
Published
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| No | Title | Action |
|---|---|---|
| 1 |
2021-Rasayan J Chem.pdf
Document Type : [PAK] Full Dokumen
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| 2 |
Turnitin-Results-RJC-6088.pdf
Document Type : [PAK] Cek Similarity
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| 3 |
Rasayan Journal of Chemistry-Scimago.pdf
Document Type :
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| 4 |
Bambang Purwono - Bukti Korespondensi.pdf
Document Type : [PAK] Bukti Korespondensi Penulis
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| 5 |
PEER REVIEW_ Bambang Purwono T2.pdf
Document Type : [PAK] Peer Review
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