ACADSTAFF UGM
| Title | : | SYNTHESIS AND PRELIMINARY EVALUATION OF SEVERAL CHALCONE DERIVATIVES AS SUNSCREEN COMPOUNDS |
| Author | : |
Prof. Drs. Jumina, Ph.D. (1) RIZKY WORO STYANINGRUM (2) Drs. Dwi Siswanta, M.Eng., Ph.D. (3) Sugeng Triono, S.Si., M.Si. (4) YOGA PRIASTOMO (5) HARIZAL (6) Prof Dr.dr. Eti Nurwening Sholikhah, M.Kes. (7) Dr. apt. Abdul Karim Zulkarnain, M.Si.,SE. (8) |
| Date | : | 28 2019 |
| Keyword | : | Chalcone, photostability, absorbance, sunscreen, broad-spectrum. Chalcone, photostability, absorbance, sunscreen, broad-spectrum. |
| Abstract | : | Four chalcone derivatives containing chloro and methoxy substituents were synthesized and pre-evaluated as broad-spectrum UV protector with intrinsic antioxidant activity. UV absorbance of chalcones 1-4 showed a wide range of UV absorbance values in UVB and UVA regions (?max= 310-360 nm) and molar absorptivity values (?= 14,000-20,000 M-1cm-1). Chalcones 3 and 4 showed better photostability than chalcones 1 and 2 because the lowering of their absorbance was smaller and slower under UVB irradiation. A combination of the spectra of chalcone derivatives 1-4 indicated that a formulation containing all four will provide a broad-spectrum sunscreen protecting the skin from UVA and UVB. |
| Group of Knowledge | : | Kimia |
| Original Language | : | English |
| Level | : | Internasional |
| Status | : |
Published
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| No | Title | Action |
|---|---|---|
| 1 |
ChemJMold_10_19261cjm_2019_624-Jumina-Published.pdf
Document Type : Bukti Published
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| 2 |
Synthesis and Preliminary Evaluation of Several Chalcone Derivatives as Sunscreen Compounds.pdf
Document Type : [PAK] Cek Similarity
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View |
| 3 |
Synthesis_and_Preliminary_Evaluation_of_Several_Ch.pdf
Document Type : [PAK] Full Dokumen
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View |
| 4 |
ChemJMold_10_19261cjm_2019_624-Jumina-Published.pdf
Document Type : [PAK] Bukti Korespondensi Penulis
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View |