ACADSTAFF UGM
| Title | : | Synthesis of 1-(2-Methoxybenzyl)-1,10-phenanthrolin-1-ium Bromide from the Gandapura Oil |
| Author | : |
Dr. Muhammad Idham Darussalam Mardjan S.Si., M.Sc. (1) Dhina Fitriastuti (2) Prof. Drs. Bambang Purwono, M.Sc., Ph.D. (3) Prof. Drs. Jumina, Ph.D. (4) |
| Date | : | 10 2019 |
| Keyword | : | phenanthroline salt,gandapura oil,alkylation,reduction,halogenations,bimolecular nucleophilic substitution. phenanthroline salt,gandapura oil,alkylation,reduction,halogenations,bimolecular nucleophilic substitution. |
| Abstract | : | This study describes a simple synthetic method to prepare 1-(2-methoxybenzyl)-1,10- phenanthrolin-1-ium bromide from gandapura oil. The salt was synthesized in four steps. Initially, commercial gandapura oil was directly subjected to the alkylation reaction under basic condition using dimethyl sulfate to give methyl 2-methxybenzoate in 86% yield. Next, the produced benzoate ester was reduced by LiAlH4 to produce 2-methoxybenzyl alcohol in 67% yield. The treatment of benzyl alcohol with phosphorus tribromide under solvent free condition produced the corresponding benzyl bromide (in 67% yield), which was directly introduced into bimolecular nucleophilic substitution reaction with 1,10- phenantroline monohydrate to finally give the desired product in 63% yield. |
| Group of Knowledge | : | Kimia |
| Original Language | : | English |
| Level | : | Nasional |
| Status | : |
Published
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| No | Title | Action |
|---|---|---|
| 1 |
484-2516-1-PB.pdf
Document Type : Bukti Published
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